In the book series, Dennee was Kahlan's adopted sister. In the television series, they were real sisters.
In the book series, James was an artist with the magical ability to trap people in the employ of Queen Milena of Tamarang. In the television series, James was an artist who could paint people into pictures and gave his life for the Seeker.
In the book series, Rachel was adopted by Chase. In the series, she was adopted by a woman named Martha.
In the book series, Shota was attracted to Richard, but loved no one. In the television series, she was in love with Zedd, with whom she had a past relationship.
In the book series, Cara was an only child who was known as Cari before being chosen to become a Mord-Sith. As a Mord-Sith, she was trained by Snake. In the series, Cara had an older sister, and was kidnapped by her schoolteacher, a disguised Mord-Sith.
In the book series, Nadine was an amateur healer who had a crush on Richard while growing up together in Hartland. She mistakenly believed that Richard loved her. In the series, Nadine was replaced by Anna, Richard's best friend growing up in Hartland. They had a serious relationship before Anna, doubting Richard, decided to move to Southhaven.
In the book series, the Boxes of Orden must be put into play before they are opened. You must open a box before one year is up after putting them into play. To open a box, you must first remove its cover. Opening one box will kill you, opening the second will kill all life, and opening the third will give you control over all life. In the television series, the Boxes of Orden must simply be placed side by side in a special formation in order to gain control over everything. Orden corrupts its user, an effect remedied only by Confession.
In the book series, the male Han is naturally stronger than the female. In the television series, there is no difference.
In the book series, the dacra is a pointed stick. In the series, it is metal star.
In the book series, the maternity spell can only be broken by the one who casts it. In the television series, the maternity spell can be broken by reforging a stronger bond between the victim and her real mother.
In the book series, Confession is final and absolute. In the television series, Confession is broken when the Confessor dies.
In the book series, the Con Dar is a magically-induced craze for revenge. In the television series, it provides increased speed, strength, and stamina, and allows the Confession of multiple people without touching them.
In the book series, the fastest recharge time for a Confessor is about two hours. In the television series, Kahlan ends up regaining her power moments after using it.
In the book series, Confession can be induced as long as the Confessor is somehow touching her victim, even through clothes. In the television series, the Confessor must be touching the victim's neck.
In the book series, Confessors wear black dresses with square necklines, while the Mother Confessor wears a white dress with a square neckline. In the television series, the necklines vary, and the highest-ranking Confessor in any given place wears white, to indicate that she is the Mother Confessor's representative.
In the books a Confessor's power will have no effect on a man if he loves her unconditionally. By the end of Wizard's First Rule, Kahlan realizes that Richard figured this out when her powers had no effect on him, however in the TV series this revelation occurs at the end of season 2.
In the book series, the bond with the Lord Rahl is dependent on the devotion. In the television series, the bond is there as long as the Lord Rahl is alive.
In the book series, the Breath of Life is a resuscitation technique. In the television series, it is a magical mist.
In the book series, Mord-Sith usually wear brown leather, and only wear red when they're training someone (the color helps hide bloodstains). They wear white when they have taken a mate. All of their leathers have the moon and star on it. Their Agiels are always red. In the television series, Mord-Sith usually wear red leather, and wear white after they finish breaking someone. Their Agiels can change color.
In the book series, nightwisps die if they are away from their kin and home for too long. In the television series, they can survive anywhere. Though this vulnerability of night wisps is alluded to in the show as well.
In the book series Richard befriends and raises an infant Gar named Gratch. In the series Gars are entirely predatory.
In Sacrifice, Mother ConfessorSerena is the Mother Confessor, who dies and the other Confessors appoint Kahlan as the Mother Confessor, whereas in the book series Kahlan has been Mother Confessor since the introduction of the characters.
In Bloodline, Jennsen is introduced, very early in the series compared to when she would have been introduced according to the book series, Season 7.
In Tears, Richard must bring the Stone of Tears to the Pillars of Creation to stop the Keeper from taking over the world of the living. This is completely contrary to the book wherein Richard must bring the stone to the Garden of Life and choose whether to seal it in the boxes again or place it on Darken Rahl, committing him to a life in the darkest recesses of the Underworld. Not only that, but the Pillars of Creation would not be due in the series until Season 7.